ATG12 (Autophagy Related 12) is a Protein Coding gene. Diseases associated with ATG12 include Stomatitis and Acute Laryngopharyngitis. Among its related pathways are Pink/Parkin Mediated Mitophagy and Autophagy - animal. Gene Ontology (GO) annotations related to this gene include Atg8 ligase activity.
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ATG12 Antibodies Catalog
Ubiquitin-like protein ATG12 is a protein in humans that is encoded by ATG12 gene. The ATG12 protein is involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.