ATG4B Proteins

ATG4B (Autophagy Related 4B Cysteine Peptidase) is a Protein Coding gene. Among its related pathways are Autophagy - animal and Autophagy Pathway. Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type peptidase activity. An important paralog of this gene is ATG4A.

The following recombinant ATG4B proteins are manufactured in house under a complete QC system by CUSABIO. They are expressed by Yeast, E.coli, Baculovirus, Mammalian cell, In Vivo Biotinylation in E.coli. Highlights of these recombinant ATG4B proteins as follow:
High purity, Low endotoxin, Multiple Tags, Animal-free, Wide applications (Cell assay, Protein-protein interaction, Drug-related studies, Enzymatic activity in vitro, Protein structure analysis, etc.)
In addition, various options on sizes, excellent technical support, and recombinant ATG4B proteins custom service will be also offered.

ATG4B Proteins Catalog

ATG4B Proteins for Oryza sativa subsp. indica (Rice)

ATG4B Proteins for Xenopus laevis (African clawed frog)

ATG4B Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

ATG4B Proteins for Bos taurus (Bovine)

ATG4B Proteins for Gallus gallus (Chicken)

ATG4B Proteins for Oryza sativa subsp. japonica (Rice)

ATG4B Proteins for Mus musculus (Mouse)

ATG4B Proteins for Arabidopsis thaliana (Mouse-ear cress)

ATG4B Background

Cysteine protease ATG4B is a protein in humans that is encoded by the ATG4B gene. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2, and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It has also an activity of the delipidating enzyme for the PE-conjugated forms.



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