ATG4C Antibodies

ATG4C (Autophagy Related 4C Cysteine Peptidase) is a Protein Coding gene. Diseases associated with ATG4C include Rem Sleep Behavior Disorder and Childhood Disintegrative Disease. Among its related pathways are Autophagy - animal and Autophagy Pathway. Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type peptidase activity. An important paralog of this gene is ATG4D.

CUSABIO produces high-quality anti-ATG4C antibodies (includes polyclonal antibodies, monoclonal antibodies, recombinant antibodies) in house with strict quality control. And they can help you discover more in your research.
These ATG4C antibodies are validated in multiple tissues with various applications and covering a broad range of life science research and drug development. They are featured with high specificity, multiple epitopes recognition, and wide species reactivity. Moreover, CUSABIO provides various options on sizes, excellent technical support and ATG4C antibodies custom service.

ATG4C Antibodies Catalog

ATG4C Antibodies for Homo sapiens (Human)

ATG4C Background

Cysteine protease ATG4C is a protein in humans that is encoded by the ATG4C gene. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. It is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). ATG4C cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It has also an activity of the delipidating enzyme for the PE-conjugated forms.



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