ATG5 Antibodies

ATG5 (Autophagy Related 5) is a Protein Coding gene. Diseases associated with ATG5 include Spinocerebellar Ataxia, Autosomal Recessive 25 and Stomatitis. Among its related pathways are Pink/Parkin Mediated Mitophagy and Autophagy - animal. Gene Ontology (GO) annotations related to this gene include Atg8 ligase activity.

CUSABIO produces high-quality anti-ATG5 antibodies (includes polyclonal antibodies, monoclonal antibodies, recombinant antibodies) in house with strict quality control. And they can help you discover more in your research.
These ATG5 antibodies are validated in multiple tissues with various applications and covering a broad range of life science research and drug development. They are featured with high specificity, multiple epitopes recognition, and wide species reactivity. Moreover, CUSABIO provides various options on sizes, excellent technical support and ATG5 antibodies custom service.

ATG5 Antibodies Catalog

ATG5 Antibodies for Homo sapiens (Human)

ATG5 Background

Autophagy protein 5 is a protein in humans that is encoded by the ATG5 gene. ATG5 is involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme that is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. ATG5 is also implicated in mitochondrial quality control after oxidative damage and subsequent cellular longevity. It plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. ATG5 is involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through the removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.